GSK-3β inhibitor 27

SKU: orb3027935

Description

GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.

Research Area

Neuroscience, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

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Key Properties

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MW	332.79
Formula	C₁₆H₁₇ClN₄O₂
SMILES	ClC1=CC=C(CN(C(/C=C\C(NC2=NNC(C)=C2)=O)=O)C)C=C1
Target	GSK-3,Beta Amyloid

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

GSK-3,Beta Amyloid

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