Cart summary

You have no items in your shopping cart.

HeE1-2Tyr

SKU: orb1297976

Description

HeE1-2Tyr is a pyridobenzothiazole-based small molecule inhibitor targeting flavivirus RNA-dependent RNA polymerase (RdRp). It demonstrates in vitro inhibitory activity against West Nile, Dengue, and SARS-CoV-2 RdRps with an IC50 of 27.6 µM. This compound is a useful research tool for antiviral studies targeting viral replication mechanisms.

Research Area

Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number2245195-67-7
MW582.67
Purity99.51% (May vary between batches)
FormulaC33H30N2O6S
SMILESOC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1cc(-c2ccccc2)c(=O)n2c3cc(OC4CCCCC4)ccc3sc12
TargetAnti-infection,SARS-CoV
SolubilityDMSO:100 mg/mL (171.62 mM)

Bioactivity

Target IC50
RdRps (SARS CoV-2):27.6 µM

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

SARSCoV, SARS-CoV, SARS coronavirus, SARS-CoV-2, West, RdRp, inhibit, Nile, flavivirus, Inhibitor, HeE1 2Tyr, HeE12Tyr, HeE-1-2Tyr, HeE1-2Tyr, Dengue
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

No computed properties available.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

HeE1-2Tyr (orb1297976)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 110.00
5 mg
$ 200.00
1 ml x 10 mM (in DMSO)
$ 240.00
10 mg
$ 310.00
25 mg
$ 510.00
50 mg
$ 700.00
100 mg
$ 970.00
DispatchUsually dispatched within 3-5 working days
Bulk Enquiry