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HIV-1 protease-IN-4

SKU: orb1982893

Description

HIV-1 protease-IN-4 (Compound II-22) is a prodrug of atazanavir designed to significantly improve its pharmacokinetic profile. In vivo rat studies demonstrate it enhances atazanavir bioavailability, increasing AUC by 5-fold and C24 by 67-fold compared to atazanavir alone, making it a valuable tool for antiviral and prodrug delivery research.

Research Area

Infectious Disease & Virology, Protein Biochemistry

Images & Validation

Key Properties

MW920.1
FormulaC48H69N7O11
TargetOthers,HIV Protease

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

HIV-1 protease-IN-4 (orb1982893)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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