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hMAO-B-IN-4

SKU: orb1685585

Description

hMAO-B-IN-4 is a potent, selective, and reversible inhibitor of human monoamine oxidase-B (IC₅₀ = 67 nM) with high BBB permeability. It is a valuable research tool for investigating MAO-B's role in neurological disorders, suitable for both in vitro enzyme assays and in vivo central nervous system studies.

Research Area

Metabolism Research, Neuroscience

Images & Validation

Key Properties

CAS Number1666119-75-0
MW320.4
Purity99.88%
FormulaC20H16O2S
SMILESO=C(\C=C\c1ccc(OCc2ccccc2)cc1)c1cccs1
TargetMAO,Monoamine Oxidase
SolubilityDMSO:3.21 mg/mL (10.02 mM)

Bioactivity

Target IC50
MAO-B (human):0.03 μM (Ki)|MAO-B (human):0.067 μM|MAO-A (human):33.82 μM
In Vitro
hMAO-B-IN-4 (0-40 μM) shows high selectivity for hMAO-B over hMAO-A, with an SI value of 504.791, and inhibits hMAO-A and hMAO-B with IC50 values of 33.821 μM and 0.067 μM, respectively.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

hMAO-B, hMAOBIN4, hMAO-B-IN-4

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  • hMAO-B-IN-4 [orb2900632]

    >98% (HPLC)

    1666119-75-0

    320.4

    C20H16O2S

    500 mg, 1 g, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg
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Key Properties

No computed properties available.

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hMAO-B-IN-4 (orb1685585)

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Available Sizes

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5 mg
$ 80.00
1 ml x 10 mM (in DMSO)
$ 90.00
10 mg
$ 100.00
25 mg
$ 160.00
50 mg
$ 240.00
100 mg
$ 370.00
200 mg
$ 500.00
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