Human CD3 epsilon Protein, Fc Tag, low endotoxin (MALS verified)

SKU: orb3002143

Description

The Asp23-Thr48 region of human CD3E is a core part of its extracellular immunoglobulin-like (Ig-like) domain. Its primary function is to act as a crucial structural scaffold, mediating proper interactions with other CD3 subunits (specifically CD3G and CD3D). It is considered as SP34 binding site.

Images & Validation

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Application Notes	This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 29.2 kDa. The protein migrates as 40-43 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Key Properties

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Expression System	HEK293
Target	CD3 epsilon
Reactivity	Human
Tag	C-Fc
Molecular Weight	29.2 kDa
Expression Region	Asp 23 - Thr 48
Purity	90%
Endotoxins	0.01 EU per μg
Conjugation	Unconjugated

Storage & Handling

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Storage	-20°C to -70°C for 12 months in lyophilized state;. -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower
Form/Appearance	Powder
Buffer/Preservatives	PBS, pH 7.4
Expiration Date	6 months from date of receipt.
Disclaimer	For research use only

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Quick Database Links

Gene Symbol

CD3 epsilon

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