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Human GFAP Protein

SKU: orb1184800

Description

GFAP (Glial fibrillary acidic protein) is a monomeric intermediate filament protein fuond in mature astrocytes and other glial cells but is not found outside the CNS. Increased GFAP immunoreactivity (or astrocytic activation) is usually viewed as an index of gliosis or a relatively slow-developing correlate of neural damage.

Images & Validation

Application Notes
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 51.9 kDa. The protein migrates as 50 kDa under reducing (R) condition (SDS-PAGE).

Key Properties

SourceHuman GFAP, His Tag (orb1184800) is expressed from E.coli cells. It contains AA Met 1 - Met 432 (Accession # P14136-1).
Expression SystemE. coli
TargetGFAP
ReactivityHuman
TagN-10×His
Molecular Weight51.9 kDa
Expression RegionMet 1 - Met 432
Purity95%
ConjugationUnconjugated

Storage & Handling

Storage-70 degrees C
Form/AppearanceLiquid
Buffer/Preservatives0.2 μm filtered solution in 20 mM Tris, 500 mM NaCl, 0.5 M Arginine, pH8.0 with trehalose as protectant. Contact us for customized formulation.
Concentration

0.469 mg/ml, volume 0.214 ml

Expiration Date6 months from date of receipt.
Dry Ice ShippingPlease note: This product requires shipment on dry ice. A dry ice surcharge will apply.
DisclaimerFor research use only

Alternative Names

Glial fibrillary acidic protein

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UniProt Details

No UniProt data available

NCBI Reference Sequences

Associated Accession Numbers
Curated reference sequences for the gene transcript and protein product
RefSeqP14136

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Protocol Information

Human GFAP Protein (orb1184800)

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