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IDH1 Inhibitor 1

SKU: orb1709444

Description

IDH1 Inhibitor 1 is a potent, selective, and orally bioavailable small molecule targeting mutant IDH1R132H/C with high selectivity over the wild-type enzyme. Its brain-penetrant properties make it a valuable tool for investigating mutant IDH1-driven mechanisms in cancers like glioma, both in cellular assays and in vivo models.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number2234285-81-3
MW450.39
FormulaC20H18F4N6O2
SMILESC[C@H](Nc1nccc(n1)N1[C@@H](CF)COC1=O)c1cn(cn1)-c1ccc(cc1)C(F)(F)F
TargetOthers,Isocitrate Dehydrogenase (IDH)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

IDH1 Inhibitor 1 (orb1709444)

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