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IKK2-IN-4

SKU: orb1693657

Description

IKK2-IN-4 (IKK2 Inhibitor VI) is a potent and selective IKK-2 inhibitor with an IC50 of 25 nM. It effectively suppresses LPS-induced TNF-α production in PBMCs, making it a valuable tool for studying NF-κB signaling in inflammatory and autoimmune disease research, both in vitro and in vivo.

Research Area

Cell Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number354811-10-2
MW261.3
Purity>99.99% (May vary between batches)
FormulaC12H11N3O2S
SMILESN(C(N)=O)C=1SC(=CC1C(N)=O)C2=CC=CC=C2
TargetTNF,IκB/IKK
SolubilityEthanol:2 mg/mL (7.65 mM);DMSO:30 mg/mL (114.81 mM)

Bioactivity

Target IC50
IKKβ:25 nM

Storage & Handling

Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

5-Phenyl-2-ureidothiophene-3-carboxylic Acid Amide, IKK2 Inhibitor IV, IKK2-IN-4, IKK2, IKK, IkB, IkB/IKK, IκB, TNF-α

Similar Products

  • IKK2-IN-4 [orb2901018]

    >98% (HPLC)

    354811-10-2

    261.3

    C12H11N3O2S

    100 mg, 200 mg, 1 g, 500 mg, 2 mg, 5 mg, 10 mg, 25 mg, 50 mg
Quality Guarantee

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Key Properties

No computed properties available.

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IKK2-IN-4 (orb1693657)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

500 μg
$ 120.00
1 mg
$ 160.00
5 mg
$ 340.00
10 mg
$ 490.00
25 mg
$ 740.00
50 mg
$ 980.00
100 mg
$ 1,290.00
200 mg
$ 1,710.00
DispatchUsually dispatched within 3-5 working days
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