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IL-2 Antibody

SKU: orb1823412

Description

Interleukin-2 (IL-2) is a T cell stimulatory cytokine that induces T cell proliferation and NK cell proliferation and activation. Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). IL-2 induces CTLA-4 and also functions as a survival factor for lymphocytes.

Images & Validation

Tested ApplicationsIHC-P
Dilution rangeImmunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
ReactivityHuman

Key Properties

Antibody TypePrimary Antibody
HostMouse
ClonalityMonoclonal
IsotypeMouse IgG1
Clone No.IL2/8712
ImmunogenA recombinant fragment of human IL2 protein was used as the immunogen for the Interleukin-2 antibody.
ConjugationUnconjugated

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
DisclaimerFor research use only

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IL-2 Antibody

IHC staining of FFPE human adrenal gland tissue with Interleukin-2 antibody (clone IL2/8712). HIER: boil tissue sections in pH9 10 mM Tris with 1 mM EDTA for 20 min and allow to cool before testing.

IL-2 Antibody

SDS-PAGE analysis of purified, BSA-free Interleukin-2 antibody (clone IL2/8712) as confirmation of integrity and purity.

UniProt Details

No UniProt data available

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Protocol Information

IHC-P
Immunohistochemistry Paraffin
View Protocol

IL-2 Antibody (orb1823412)

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20 μg
$ 410.00
100 μg
$ 780.00
DispatchUsually dispatched within 5-10 working days
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