IFN gamma Antibody

SKU: orb2639890

Description

Recognizes a protein of 20-25kDa, identified as human interferon. This mAb is specific to human IFNg and recognizes both recombinant and native human IFNg. T lymphocytes and NK cells mainly produce IFNg. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses, including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak anti-viral and anti-proliferative activity, and potentiates the antiviral and anti-tumor effects of IFNa/b (type I interferon).

Images & Validation

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Tested Applications	IHC-P
Dilution range	Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
Reactivity	Human
Application Notes	Optimal dilution of the IFN gamma antibody should be determined by the researcher.

Key Properties

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Antibody Type	Primary Antibody
Host	Mouse
Clonality	Monoclonal
Isotype	Mouse IgG2b, kappa
Clone No.	IFNG/466
Immunogen	Human recombinant protein was used as the immunogen for the IFN gamma antibody.
Purification	Protein G affinity chromatography
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Disclaimer	For research use only

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IHC testing of FFPE human renal cell carcinoma with IFN gamma antibody (clone IFNG/466). Required HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH9.0, for 10-20 min.

IHC testing of FFPE human testis with IFN gamma antibody (clone IFNG/466). Required HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH9.0, for 10-20 min.

SDS-PAGE Analysis of Purified, BSA-Free IFN gamma Antibody (clone IFNG/466). Confirmation of Integrity and Purity of the Antibody.

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UniProt

P01579

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No UniProt data available

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Protocol Information

IHC-P

Immunohistochemistry Paraffin

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