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IQ-1S

SKU: orb2814154

Description

IQ-1S is a potent small molecule inhibitor of NF-κB and AP-1 signaling pathways, with an IC50 of 1.8 µM. It functions by binding with high affinity to JNK isoforms, particularly JNK3 (Kd 87 nM), making it a valuable tool for studying inflammation, apoptosis, and neuronal death in cellular and animal models.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number1421610-21-0
MW269.23
FormulaC15H8N3NaO
SMILES[O-]N=C1C2=C(C3=CC=CC=C13)N=C4C=CC=CC4=N2.[Na+]
TargetJNK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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IQ-1S (orb2814154)

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