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ITK inhibitor 2

SKU: orb1709389

Description

Compound 4 is a highly potent and selective inhibitor of interleukin-2-inducible T-cell kinase (ITK), exhibiting an IC50 value of 2 nM. This small molecule is a valuable research tool for investigating T-cell signaling and related immunology in both cellular and animal models of inflammation and autoimmune disease.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number1309784-09-5
MW435.56
Purity99.67% (May vary between batches)
FormulaC25H33N5O2
SMILESCC1(C)CC2=C(C(=NN2)C=3NC=4C(C3)=CC=C(N(C([C@H](C)N5CCOCC5)=O)C)C4)CC1
TargetTyrosine Kinases
SolubilityDMSO:110 mg/mL (252.55 mM)

Bioactivity

Target IC50
ITK:2 nM

Storage & Handling

Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

ITK inhibitor 2

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Key Properties

No computed properties available.

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Protocol Information

ITK inhibitor 2 (orb1709389)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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1 mg
$ 100.00
5 mg
$ 170.00
10 mg
$ 240.00
25 mg
$ 500.00
50 mg
$ 830.00
100 mg
$ 1,110.00
200 mg
$ 1,470.00
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