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Jatrorrhizine

SKU: orb1303544

Description

Jatrorrhizine (neprotin) is a protoberberine alkaloid derived from plants like Enantia chlorantha. It exhibits antimicrobial and antifungal properties and acts as a noncompetitive monoamine oxidase inhibitor (IC50 4 µM for MAO-A, 62 µM for MAO-B). This compound is used in research on neurochemistry and infectious diseases in vitro.

Research Area

Infectious Disease & Virology, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number3621-38-3
MW338.38
Purity98.59%
FormulaC20H20NO4
SMILESO(C)C=1C=C2C=3[N+](=CC=4C(C3)=CC=C(OC)C4OC)CCC2=CC1O
TargetMAO,Antibacterial,Cholinesterase (ChE),5-HT Receptor
SolubilityChloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble;DMSO:6.67 mg/mL (19.71 mM)

Bioactivity

Target IC50
MAO-A:4 μm|MAO-B:62μm

Storage & Handling

Storagekeep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Yatrorizine, quaternary isoquinoline, Serotonin Receptor, 5-hydroxytryptamine Receptor, 5HTReceptor, 5-HT Receptor, 5HT Receptor, AChE, alkaloid, Bacterial, antiplasmodial, antiamoebic, antidepressant, antidepressant-like, antioxidant, antimicrobial, Alzheimer's disease, Cholinesterase (ChE), depressive disorder, E. histolytica, Cytotoxic, inhibit, Jatrorrhizine, neuroprotective, neprotin, Inhibitor, MAO-A, MAO-B, falciparum

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Key Properties

No computed properties available.

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Jatrorrhizine (orb1303544)

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Available Sizes

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2 mg
$ 80.00
5 mg
$ 90.00
10 mg
$ 120.00
25 mg
$ 180.00
50 mg
$ 240.00
100 mg
$ 340.00
200 mg
$ 490.00
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