Juglone (Standard)

SKU: orb3139237

Description

Juglone (Standard) is a reference standard for research and analysis in studies involving Juglone. Juglone (Regianin) is a natural naphthoquinone found in the black walnut (J. nigra) and other plants in the Juglandaceae family. Juglone also irreversibly inhibits peptidyl-prolyl cis/trans isomerases of the parvulin family, including human Pin1, yeast Ess1/Ptf1, and E. coli parvulin (Ki = 55.9 nM). Juglone also blocks transcription by RNA polymerases I, II, and III (IC50s = 2-7 μM) and attenuates kidney fibrosis in rats treated with unilateral ureteral obstruction, both through Pin1-independent mechanisms.

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Key Properties

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CAS Number	481-39-0
MW	174.15
Formula	C₁₀H₆O₃
SMILES	Oc1cccc2C(=O)C=CC(=O)c12
Target	Others

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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