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Keap1-Nrf2-IN-11

SKU: orb1744739

Description

Keap1-Nrf2-IN-11 (Compound 6k) is a potent, high-affinity Keap1-Nrf2 inhibitor (KD = 0.21 nM) that promotes Nrf2 nuclear translocation to suppress ROS, NO, and TNF-α production. This mechanism supports its application in cellular and animal models for studying inflammatory and oxidative stress-related pathways.

Research Area

Immunology & Inflammation, Signal Transduction

Images & Validation

Key Properties

CAS Number2796292-75-4
MW765.9
FormulaC36H43N7O8S2
SMILESCCN1CCN(CC1)CCC(=O)NC2=CC=C(C=C2)S(=O)(=O)N(CC(=O)N)C3=CC=C(C4=CC=CC=C43)N(CC(=O)N)S(=O)(=O)C5=CC=C(C=C5)OC
TargetOthers,NO Synthase,ROS Kinase,Nrf2

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Keap1-Nrf2-IN-11 (orb1744739)

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