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Kuwanon U

SKU: orb2564111

Description

Kuwanon U, a bioactive compound from Morus alba, acts as a dual cholinesterase inhibitor and a SERCA1 ATPase antagonist. Its research applications include investigating mechanisms related to diabetes mellitus and exploring antimicrobial activity in in vitro studies.

Research Area

Neuroscience

Images & Validation

Key Properties

CAS Number123702-95-4
MW438.51
FormulaC26H30O6
SMILESO=C1C=2C(O[C@@H](C1)C3=CC(C/C=C(/CCC=C(C)C)\C)=C(OC)C=C3O)=CC(O)=CC2O
TargetCholinesterase (ChE)

Bioactivity

Target IC50
Butyrylcholinesterase:9.59 µM (Ki)|Butyrylcholinesterase:10.11 µM|Acetylcholinesterase:6.48 µM (Ki)|Acetylcholinesterase:19.69 µM
In Vitro
Kuwanon U is a potent cholinesterase inhibitor exhibiting inhibitory activity against acetylcholinesterase and butyrylcholinesterase with IC50 values of 19.69 µM and 10.11 µM and Ki values of 6.48 µM and 9.59 µM, respectively.

Storage & Handling

Storagestore at low temperature,keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

acetylcholinesterase, 4'-methoxykuwanon E, cholinesterase

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Key Properties

No computed properties available.

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Kuwanon U (orb2564111)

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1 mg
$ 720.00
5 mg
$ 1,470.00
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