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Londamocitinib

SKU: orb1709376

Description

Londamocitinib (JAK1-IN-7) is a potent and selective Janus kinase 1 (JAK1) inhibitor exhibiting anti-inflammatory properties. It is utilized in research to investigate JAK-STAT signaling pathways in inflammatory and autoimmune disease models, both in cellular assays and preclinical studies.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number2241039-81-4
MW599.65
Purity99.56% (May vary between batches)
FormulaC28H31F2N7O4S
SMILESCOC[C@@H](N1CCN(C)CC1)C(=O)Nc1cccc2c(c[nH]c12)-c1nc(Nc2cccc(c2F)S(C)(=O)=O)ncc1F
TargetJAK
SolubilityDMSO:70 mg/mL (116.73 mM);10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (5.5 mM)

Storage & Handling

Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

JAK1-IN-7, JAK1, AZD4604
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Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

Londamocitinib (orb1709376)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 230.00
5 mg
$ 510.00
1 ml x 10 mM (in DMSO)
$ 640.00
10 mg
$ 670.00
25 mg
$ 1,000.00
50 mg
$ 1,270.00
100 mg
$ 1,690.00
DispatchUsually dispatched within 3-5 working days
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