Luteolin-7-rutinoside

SKU: orb1709233

Description

Luteolin-7-rutinoside is a bioactive flavonoid that mitigates LPS-induced acute liver injury in research models. It functions by inhibiting the PI3K/AKT/AMPK/NF-κB pathways and reducing pro-inflammatory cytokines like TNF-α, IL-6, and IL-1β, making it a valuable tool for studying inflammation and hepatotoxicity in vitro and in vivo.

Research Area

Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	20633-84-5
MW	594.52
Purity	99.99% (May vary between batches)
Formula	C₂₇H₃₀O₁₅
SMILES	O=C1C=2C(OC(=C1)C3=CC(O)=C(O)C=C3)=CC(O[C@@H]4O[C@H](CO[C@H]5[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O5)[C@@H](O)[C@H](O)[C@H]4O)=CC2O
Target	IL Receptor,NF-κB,TNF,Akt,AMPK,PI3K
Solubility	DMSO:80 mg/mL (134.56 mM)

Bioactivity

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In Vitro	Luteolin-7-rutinoside (10 μg/mL) inhibited T cell proliferation, reducing proliferative capacity by approximately 47%. The inhibitory effect of Luteolin-7-rutinoside (40 μg/mL) on T cell proliferation was essentially equivalent to that of the 20 μg/mL concentration group, with the compound's inhibitory activity exhibiting dose dependency . Read more...

Storage & Handling

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Storage	keep away from direct sunlight,keep away from moisture \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Luteolin-7-rutinoside, Luteolin7rutinoside, Luteolin 7 rutinoside

Quality Guarantee

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Compound Identifiers

PubChem CID

10461109 ↗

Key Properties

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No computed properties available.

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