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MAO-B-IN-30

SKU: orb2281147

Description

MAO-B-IN-30 is a brain-penetrant, selective MAO-B inhibitor with dual MAO-A/B activity and antiproliferative effects. It reduces pro-inflammatory markers like TNF-α, IL-6, and NF-κB, making it a useful research tool for studying Parkinson's disease mechanisms in both cellular and animal models.

Research Area

Cell Biology, Metabolism Research, Neuroscience, Signal Transduction

Images & Validation

Key Properties

CAS Number82973-15-7
MW344.16
Purity98.31%
FormulaC15H10BrN3O2
SMILESO=C(NN=C1C(=O)NC=2C=CC=CC21)C3=CC=C(Br)C=C3
TargetMAO,TNF,Monoamine Oxidase,NF-κB

Bioactivity

Target IC50
MAO-B:0.082 μM|MAO-A:19.176 μM
In Vitro
In SH-SY5Y cells, MAO-B-IN-30 ( 0-100 μM ; inhibited cell growth and non-cytotoxic.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

MAOBIN30, MAO-B, MAO-A, IL-6, NF-kB, NFkB, NFκB, NF-κB, TNF-α
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

MAO-B-IN-30 (orb2281147)

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5 mg
$ 80.00
10 mg
$ 100.00
25 mg
$ 160.00
50 mg
$ 220.00
100 mg
$ 300.00
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