MC-Val-Cit-PAB-Exatecan

SKU: orb2279085

Description

MC-Val-Cit-PAB-Exatecan (MC-Val-Cit-PAB-DX8951) consists of a cytotoxin, the topoisomerase I inhibitor DX-8951, and a linker sensitive to cathepsin, forming a drug-linker conjugate for antibody-drug conjugates (ADCs).

Research Area

Molecular Biology

Images & Validation

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Key Properties

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CAS Number	2504068-28-2
MW	1034.09
Purity	98.03%
Formula	C₅₃H₆₀FN₉O₁₂
SMILES	N(C(OCC1=CC=C(NC([C@@H](NC([C@@H](NC(CCCCCN2C(=O)C=CC2=O)=O)[C@H](C)C)=O)CCCNC(N)=O)=O)C=C1)=O)[C@@H]3C4=C5C(C=6N(C5)C(=O)C7=C(C6)[C@](CC)(O)C(=O)OC7)=NC=8C4=C(CC3)C(C)=C(F)C8
Target	Topoisomerase,Drug-Linker Conjugates for ADC

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Gene Symbol

Topoisomerase,Drug-Linker Conjugates for ADC

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