Cart summary

You have no items in your shopping cart.

MC-Val-Cit-PAB

SKU: orb1302049

Description

MC-Val-Cit-PAB is a protease-cleavable linker utilized in the construction of antibody-drug conjugates (ADCs), such as the clinically approved brentuximab vedotin. It enables targeted drug delivery and release in both in vitro and in vivo research models for oncology and targeted therapy development.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number159857-80-4
MW572.65
Purity98.24% (May vary between batches)
FormulaC28H40N6O7
SMILES[C@@H](NC([C@@H](NC(CCCCCN1C(=O)C=CC1=O)=O)[C@H](C)C)=O)(C(NC2=CC=C(CO)C=C2)=O)CCCNC(N)=O
TargetADC Linker,AChR
SolubilityDMSO:22 mg/mL (38.42 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8.73 mM)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

inhibit, Inhibitor, MCValCitPAB, MC-Val-Cit-PAB, MC Val Cit PAB, Antibody-drug conjugates linkers, ADCLinker, ADC Linker, ADC Linkers

Similar Products

  • MC-VC(S)-PABQ-Tubulysin M [orb1988044]

    2055896-86-9

    1283.6

    C66H96N11O13S

    100 mg, 500 mg
  • Paclitaxel-MVCP [orb1985502]

    2119034-12-5

    1452.58

    C76H89N7O22

    100 mg, 500 mg
  • Mc-Val-Cit-PAB-Cl [orb1307356]

    99.79% (May vary between batches)

    1639351-92-0

    591.1

    C28H39ClN6O6

    100 mg, 5 mg, 200 mg, 1 mg, 10 mg, 25 mg, 50 mg
  • MC-Val-Cit-PAB-Amide-TLR7 agonist 4 [orb1982913]

    97.70% (May vary between batches)

    2413016-49-4

    1041.2

    C52H72N12O11

    5 mg, 50 mg, 25 mg, 10 mg, 1 mg
  • MC-Val-Cit-PAB-Sunitinib [orb2945801]

    954.12

    C50H66FN10O8

    10 mg, 50 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

No computed properties available.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

MC-Val-Cit-PAB (orb1302049)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

25 mg
$ 70.00
50 mg
$ 70.00
DispatchUsually dispatched within 3-5 working days
Bulk Enquiry