mDPR-Val-Cit-PAB-MMAE TFA

SKU: orb2283415

Description

mDPR-Val-Cit-PAB-MMAE TFA is a cleavable drug-linker conjugate for constructing Antibody-Drug Conjugates (ADCs). It incorporates the potent antimitotic agent MMAE, which is released upon protease cleavage, enabling targeted cytotoxicity in both in vitro and in vivo cancer research models.

Images & Validation

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Key Properties

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CAS Number	2185872-76-6
MW	1403.58
Formula	C₆₇H₁₀₁F₃N₁₂O₁₇
SMILES	C(C(O)=O)(F)(F)F.[C@H]([C@H](C(N[C@@H]([C@@H](O)C1=CC=CC=C1)C)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(C(OCC3=CC=C(NC([C@@H](NC([C@@H](NC([C@H](CN)N4C(=O)C=CC4=O)=O)[C@@H](C)C)=O)CCCNC(N)=O)=O)C=C3)=O)C)C(C)C)=O)[C@@H](C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]
Target	Drug-Linker Conjugates for ADC

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

171042997 ↗

Key Properties

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No computed properties available.

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