N-Deshydroxyethyl Dasatinib

SKU: orb1987684

Description

N-Deshydroxyethyl Dasatinib is a metabolite of the anticancer drug Dasatinib and a key component in the SNIPER molecule BMS-354825, which targets ABL for degradation. This research compound is utilized in biochemical studies to investigate targeted protein degradation strategies in cancer and immunological research, both in vitro and in vivo.

Research Area

Cell Biology, Metabolism Research

Images & Validation

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Key Properties

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CAS Number	910297-51-7
MW	443.95
Purity	95.96% (May vary between batches)
Formula	C₂₀H₂₂ClN₇OS
SMILES	N(C1=CC(=NC(C)=N1)N2CCNCC2)C=3SC(C(NC4=C(C)C=CC=C4Cl)=O)=CN3
Target	Drug Metabolite,IAP
Solubility	10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.51 mM);DMSO:49.5 mg/mL (111.5 mM)

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Drug Metabolite, DrugMetabolite, BCR-ABL, IAP, N-Deshydroxyethyl BMS 354825, N-Deshydroxyethyl BMS354825, N-Deshydroxyethyl BMS-354825, N-Deshydroxyethyl Dasatinib

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Compound Identifiers

PubChem CID

11669430 ↗

Key Properties

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No computed properties available.

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