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Nanchangmycin

SKU: orb1685643

Description

Nanchangmycin A is a polyether antibiotic structurally related to dianemycin. It exhibits potent, broad-spectrum activity against nematodes and insects in research settings, while showing selectivity by being non-toxic to mammals and plants in experimental studies.

Research Area

Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number65101-87-3
MW889.1
Purity99.13% (May vary between batches)
FormulaC47H77NaO14
SMILESC[C@H]1[C@@]2(O[C@]([C@@]3([H])O[C@](O)([C@@H](C[C@@H]3C)C)CO)([H])C[C@@H]2C)O[C@]([C@]4(O[C@]5(O[C@]([C@@H]([C@H](C5)O)C)([H])[C@@H](C)/C=C(C)/C([C@H](C)C[C@H](C)C([O-])=O)=O)CC4)C)([H])C[C@@H]1O[C@H]6O[C@@H]([C@H](CC6)OC)C.[Na+]
TargetAntibacterial,Anti-infection,Antibiotic
SolubilityH2O:< 1 mg/mL (insoluble or slightly soluble);DMSO:88.9 mg/mL (99.99 mM);10% DMSO+90% Corn Oil:3.3 mg/mL (3.71 mM)

Bioactivity

In Vivo
Nanchangmycin, a growth promoter in poultry, cures coccidiosis in chickens. Nanchangmycin, a bacterially-derived natural product, blocks ZIKV and DENV infection potently in diverse cell types.
In Vitro
Nanchangmycin resists gram-positive bacteria.
Cell Research
5×10E3 U2OS cells were plated in 25ul media per well in 384-well plates and cultured for 24 hours. Add 50 nl of Nanchangmycin, which is 0.7uM dissolved in 0.2% DMSO, to each well incubating for 1 hour.

Storage & Handling

Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Antibiotic, Antibacterial, Bacterial, inhibit, Inhibitor, Nanchangmycin, Nanchangmycin A

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  • Nanchangmycin [orb1224343]

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    1 g, 500 mg, 50 mg, 200 mg, 100 mg, 10 mg
Quality Guarantee

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Key Properties

No computed properties available.

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Nanchangmycin (orb1685643)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 100.00
5 mg
$ 180.00
1 ml x 10 mM (in DMSO)
$ 260.00
10 mg
$ 270.00
25 mg
$ 490.00
DispatchUsually dispatched within 5-10 working days
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