Neuroprotective agent 11

SKU: orb3135636

Description

Neuroprotective agent 11 (Compound 1a) is an orally active polyphenolic compound that offers significant protection against cerebral ischemia. Its primary activities include inhibiting neuronal inflammation and apoptosis, reducing cerebral infarct size, and improving behavioral symptoms in mice with cerebral ischemia. The mechanism involves downregulating inflammatory factors (iNOS, COX-2) and apoptotic proteins (cleaved-Caspase3, p53). Neuroprotective agent 11 is applicable for research in ischemia-related brain diseases, such as ischemic stroke.

Images & Validation

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Key Properties

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CAS Number	3081915-81-0
MW	606.57
Formula	C₃₂H₃₀O₁₂
SMILES	O[C@H]1[C@@H](C=2C(O[C@@H]1C3=CC(O)=C(O)C=C3)=C(CC)C(O)=CC2O)C4=C5C(C[C@H](O)[C@H](O5)C6=CC(O)=C(O)C=C6)=C(O)C=C4O
Target	NO Synthase,MDM-2/p53,COX,Caspase

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

NO Synthase,MDM-2/p53,COX,Caspase

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