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NF-κB/MAPK-IN-2

SKU: orb2945845

Description

NF-κB/MAPK-IN-2 is a dual-pathway inhibitor that suppresses LPS-induced pro-inflammatory signaling by reducing phosphorylation of key proteins (p65, IκB, p38, JNK, ERK) and cytokine release (TNF-α, IL-6). It has demonstrated utility in cellular models of inflammation and shows research potential for investigating septic shock mechanisms.

Research Area

Signal Transduction

Images & Validation

Key Properties

MW827.056
FormulaC49H66N2O9
SMILESCCOC(=O)C1=NOC2=C1C[C@]3([C@H]([C@]2(C)COC(=O)CCC(=O)N4CCOCC4)CC[C@@]5([C@@H]3CC=C6[C@]5(CC[C@@]7([C@H]6CC(CC7)(C)C)C(=O)OCC8=CC=CC=C8)C)C)C
Targetp38 MAPK,NF-κB

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

NF-κB/MAPK-IN-2 (orb2945845)

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