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Nimesulide

SKU: orb1309658

Description

Nimesulide (R805) is a COX-2 preferential NSAID used in research for its analgesic and antipyretic effects. It is employed in vitro and in vivo to study inflammation, pain mechanisms, and cyclooxygenase enzyme selectivity.

Research Area

Immunology & Inflammation, Neuroscience

Images & Validation

Key Properties

CAS Number51803-78-2
MW308.31
Purity98.00%
FormulaC13H12N2O5S
SMILESO(C1=C(NS(C)(=O)=O)C=CC(N(=O)=O)=C1)C2=CC=CC=C2
TargetCOX
SolubilityDMSO:55 mg/mL (178.39 mM);Ethanol:7.7 mg/mL (24.97 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.49 mM)

Bioactivity

Target IC50
COX-2:26 μM

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

R805, R-805, R 805, Nimesulide, inhibit, Inhibitor, Cyclooxygenase, COX-2, COX

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Key Properties

No computed properties available.

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Nimesulide (orb1309658)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

25 mg
$ 70.00
50 mg
$ 80.00
1 ml x 10 mM (in DMSO)
$ 90.00
100 mg
$ 90.00
200 mg
$ 100.00
DispatchUsually dispatched within 3-5 working days
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