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Ombuoside

SKU: orb1297258

Description

Ombuoside, a flavonoid glycoside isolated from Gynostemma pentaphyllum, exhibits notable antifungal and antioxidant activities as demonstrated in DPPH, TEAC, and reducing power assays. This compound is utilized in research exploring oxidative stress and microbial pathogenesis in various in vitro models.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Protein Biochemistry, Signal Transduction

Images & Validation

Key Properties

CAS Number20188-85-6
MW638.57
Purity99.80% (May vary between batches)
FormulaC29H34O16
SMILESCOc1cc(O)c2c(c1)oc(-c1ccc(OC)c(O)c1)c(O[C@@H]1O[C@H](CO[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@H]1O)c2=O
TargetCaspase,JNK,ROS,Antibacterial,Antifungal,ERK,Apoptosis
Solubility10% DMSO+90% Saline:1.67 mg/mL (2.62 mM);DMSO:65 mg/mL (101.79 mM)

Bioactivity

In Vitro
Ombuoside and the synthetic derivatives octa-acetylOmbuoside, ombuine and retusine were tested for antimicrobial activity against several strains of Gram-positive and Gram-negative bacteria and the yeast Candida albicans, using the agar diffusion method. The flavonol glycoside Ombuoside and the respective aglycone ombuine, both exhibited moderated activity against Corynebacterium diphtheria, Staphylococcus aureus, Escherichia coli and Candida albicans. To a lesser degree, octaacetylOmbuoside and retusine showed activity against the Gram-positive bacteria C. diphtheria and S. aureus, but proved to be inactive against Gram-negative bacteria and Candida albicans

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

antioxidant, antimicrobial, Antifection, Bacterial, bacteria, gram-negative, Gynostemma pentaphyllum, Inhibitor, Parkinson?s disease, Ombuin-3beta-rutinoside, Ombuin-3b-rutinoside, Ombuin-3β-rutinoside, Ombuoside, inhibit, ros, radical
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Key Properties

No computed properties available.

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Ombuoside (orb1297258)

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Available Sizes

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1 mg
$ 80.00
5 mg
$ 140.00
1 ml x 10 mM (in DMSO)
$ 160.00
10 mg
$ 190.00
25 mg
$ 440.00