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Perillartine

SKU: orb1222384

Description

Peryllartine is a sweetener that is about 2000 times as sweet as sucrose. Perillartine is the oxime of perillaldehyde.

Images & Validation

Key Properties

CAS Number30950-27-7
MW165.23
Purity>98% (HPLC)
FormulaC10H15NO
SMILESCC(=C)C1CCC(=CC1)C=NO
TargetOthers
SolubilityDMSO : ≥ 100 mg/mL 605.22 mM; H2O : < 0.1 mg/mL

Bioactivity

In Vitro
The responses of the monomeric Tas1r2 subunits of human, rhesus monkey, squirrel monkey and mouse to Perillartine are examined, respectively. The human, rhesus monkey and squirrel monkey Tas1r2 subunits can be activated by Perillartine, while mouse Tas1r2 can not. The insensitivity of human, rhesus monkey, squirrel monkey and mouse Tas1r2 subunits to cyclamate precludes the probable involvement of Tas1r3 subunit in the assay. Replacement of the mouse Tas1r2 with rhesus monkey Tas1r2 (rhTas1r2/mTas1r3) leads to a gain of response to Perillartine. The dose-response curve show the efficacy of responses of the Tas1r2 subunits among species: hTAS1R2>rhTas1r2>smTas1r2>mTas1r2. These results demonstrate that the monomeric Tas1r2 subunit can be activated by Perillartine in a species-dependent manner.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Peryllartine | AI3-52127 | Perilla sugar, Perillartine

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    99.57%

    30950-27-7

    165.23

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    50 mg, 1 ml x 10 mM (in DMSO)
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(Recommended: An additional animal making an allowance for loss during the experiment)

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