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Phthalimidinoglutarimide-piperidine-NH-Boc

SKU: orb2565532

Description

This compound is a thalidomide-based cereblon (CRBN) ligand-linker conjugate, serving as a key intermediate for constructing PROTAC degraders. It is widely used in chemical biology and drug discovery research for the targeted protein degradation of various targets in both cellular and in vivo models.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2229720-55-0
MW442.51
FormulaC23H30N4O5
SMILESO=C1N(CC=2C1=CC=C(C2)N3CCC(NC(OC(C)(C)C)=O)CC3)C4C(=O)NC(=O)CC4
TargetE3 Ligase Ligand-Linker Conjugates

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

Phthalimidinoglutarimide-piperidine-NH-Boc (orb2565532)

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