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PIYLGGVFQ

SKU: orb2813689

Description

PIYLGGVFQ is a peptide inhibitor of TNF-α that blocks its pro-apoptotic signaling, NF-κB activation, and nuclear translocation. It has shown efficacy in reducing arthritis severity in the collagen-induced arthritis (CIA) mouse model, supporting its use in researching inflammatory and autoimmune diseases.

Research Area

Cell Biology, Signal Transduction

Images & Validation

Key Properties

TargetNF-κB,Apoptosis,TNF
Molecular Weight993.16

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

PIYLGGVFQ (orb2813689)

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