PKC β pseudosubstrate

This cell-permeable peptide inhibitor selectively targets protein kinase C with an IC50 of ~0.5 µM. It is derived from the PKC pseudosubstrate domain and utilizes an Antennapedia carrier for efficient cellular uptake, where intracellular reduction releases the active inhibitor. It is widely used in both in vitro and in vivo studies to investigate PKC signaling in cancer, neuroscience, and cardiovascular research.