Recombinant Podocalyxin Antibody

SKU: orb699653

Description

Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.

Research Area

Epigenetics

Images & Validation

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Tested Applications	ELISA
Dilution Range	ELISA: order Ab without BSA for coating
Reactivity	Human
Application Notes	Optimal dilution of the recombinant Podocalyxin antibody should be determined by the researcher.

Key Properties

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Antibody Type	Primary Antibody
Host	Mouse
Clonality	Recombinant
Isotype	Mouse IgG1, kappa
Clone No.	rPODXL/2184
Immunogen	A portion of amino acids 310-447 from the human protein was used as the immunogen for the recombinant Podocalyxin antibody.
Purification	Protein G affinity chromatography
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives	0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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SDS-PAGE analysis of purified, BSA-free recombinant Podocalyxin antibody (clone rPODXL/2184) as confirmation of integrity and purity.

Quick Database Links

UniProt

O00592

UniProt Details

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No UniProt data available

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Protocol Information

ELISA

Enzyme-linked Immunosorbent Assay (EIA)

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