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Prim-O-glucosylcimifugin

SKU: orb1303725

Description

Prim-O-glucosylcimifugin is a small molecule that suppresses TNF-α-induced smooth muscle cell proliferation by inducing cell cycle arrest at the G0/G1 phase. This activity makes it a candidate for research in vascular pathologies, such as atherosclerosis and restenosis, in both cellular and animal models.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Neuroscience, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number80681-45-4
MW468.45
Purity99.92% (May vary between batches)
FormulaC22H28O11
SMILESCOc1c2C[C@H](Oc2cc2oc(CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)cc(=O)c12)C(C)(C)O
TargetJAK,TNF,NO Synthase,COX
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.27 mM);DMSO:125 mg/mL (266.84 mM)

Storage & Handling

Storagestore at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

COX, Cyclooxygenase, Cimifugin 7-glucoside, Cimifugin b-D-glucopyranoside, Cimifugin beta-D-glucopyranoside, Cimifugin β-D-glucopyranoside, Inhibitor, inhibit, NOSynthase, NOS, Nitric oxide synthases, NO Synthase, Prim O glucosylcimifugin, PrimOglucosylcimifugin, Prim-O-glucosylcimifugin, TNF-α

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Key Properties

No computed properties available.

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Prim-O-glucosylcimifugin (orb1303725)

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% DMSO +
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% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 100.00
1 ml x 10 mM (in DMSO)
$ 170.00
5 mg
$ 170.00
10 mg
$ 270.00
25 mg
$ 420.00
50 mg
$ 600.00
100 mg
$ 830.00
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