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Recombinant Human Interleukin-1 Receptor Antagonist Protein
SKU: orb1906339
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Description
Research Area
Immunology & Inflammation; Pharmacology & Drug Discovery
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Key Properties
−| Source | Escherichia coli |
|---|---|
| Expression System | Escherichia coli |
| Biological Activity | Fully biologically active when compared to standard. The ED50 as determined by inhibiting IL-1α-dependent proliferation of murine D10S cells is less than 40 ng/ml, corresponding to a specific activity of > 2.5 x104 IU/mg in the presence of 50 pg/ml rHuIL-1α. |
| Endotoxins | Less than 1 EU/ug of rHuIL-1RA as determined by LAL method. |
| MW | Approximately 17.1 kDa, a single non-glycosylated polypeptide chain containing 152 amino acids. |
| Purity | > 96 % by SDS-PAGE and HPLC analyses. |
| Protein Sequence | RPSGRKSSKM QAFRIWDVNQ KTFYLRNNQL VAGYLQGPNV NLEEKIDVVP IEPHALFLGI HGGKMCLSCV KSGDETRLQL EAVNITDLSE NRKQDKRFAF IRSDSGPTTS FESAACPGWF LCTAMEADQP VSLTNMPDEG VMVTKFYFQE DE |
Storage & Handling
−| Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution. |
|---|---|
| Form/Appearance | Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4. |
| Expiration Date | 6 months from date of receipt. |
| Disclaimer | For research use only |
Alternative Names
−IL-1RN, IRAP
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WB analysis of orb1906339.
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Recombinant Human Interleukin-1 Receptor Antagonist Protein (orb1906339)
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