RIP2 Kinase Inhibitor 4

SKU: orb1691211

Description

RIP2 Kinase Inhibitor 4 is a potent and selective RIPK2 PROTAC degrader (pIC50 = 8) that suppresses TNF-α release. This compound is a valuable tool for studying NOD signaling in inflammatory and autoimmune disease research, applicable in both cellular and in vivo models.

Research Area

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	2126803-41-4
MW	1045.23
Formula	C₅₀H₆₆F₂N₁₄O₇S
SMILES	CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@H](C[C@H]1C(=O)Nc1c(F)cccc1F)NC(=O)c1cnc(cn1)N1CCN(CCCOc2cc3ncnc(Nc4n[nH]c(C)c4C)c3cc2S(=O)(=O)C(C)(C)C)CC1)C(C)(C)C \|@@:70\|
Target	RIP kinase,PROTACs,Others

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

134496515 ↗

Key Properties

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No computed properties available.

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