RORA (C) Antibody, Rabbit Polyclonal

SKU: orb66984

Description

Rabbit polyclonal to RORA.Nuclear receptor ROR-alpha ORA) is an orphan nuclear receptor that belongs to the nuclear hormone receptor family, NR1 subfamily. RORA binds DNA as a monomer to hormone response elements (HRE) containing a single core motif half-site preceeded by a short A-T-rich sequence. RORA regulates a number of genes involved in lipid metabolism, such as apolipoproteins AI, APOA5, CIII, CYP71 and PPARgamma; in cerebellum and photoreceptor development including PCP2, OPN1SW, OPN1SM AND ARR3; in circadian rhythm with BMAL1, and skeletal muscle development with MYOD1. RORA is a possible receptor for cholesterol or one of its derivatives.

Research Area

Developmental Biology, Epigenetics

Images & Validation

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Item 1 of 1

Tested Applications	WB
Dilution range	WB:1:1000-1:5000
Reactivity	Human, Mouse

Key Properties

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Host	Rabbit
Clonality	Polyclonal
Immunogen	C-terminal region of mouse RORA
Molecular Weight	59
Purity	Affinity purification
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives	0.01% NaN3
Disclaimer	For research use only

Alternative Names

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anti-RORA antibody,anti-Nuclear receptor RORalpha antibody,anti-Nuclear receptor RZRalpha antibody,anti-Nuclear receptor subfamily 1 group F member 1 antibody,anti-Retinoidrelated orphan receptoralpha antibody,anti-Nr1f1 antibody,anti-Rzra antibody

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Western blot analysis of total cell extracts from human Jurkat(Lane1) and mouse thymus(Lane2) using RORA antibody

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UniProt

P51448

UniProt Details

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No UniProt data available

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Protocol Information

Western Blot (IB, immunoblot)

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