Sarilumab Antibody

SKU: orb1980721

Description

Sarilumab (SAR-153191) is a human IgG1 monoclonal antibody that acts as a potent IL-6 receptor antagonist, blocking IL-6-mediated signaling to reduce inflammation. It is applied in rheumatoid arthritis research, with studies demonstrating its efficacy in both in vitro assays and in vivo animal models of inflammatory disease.

Research Area

Immunology & Inflammation

Images & Validation

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Key Properties

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CAS Number	1189541-98-7
MW	144.12 kDa
Purity	98.4% (SEC-HPLC)
Target	IL Receptor

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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IL-6, ILReceptor, IL Receptor, anti-IL-6Rα, REGN-88, SAR-153191, Sarilumab (anti-IL-6Rα)

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Quick Database Links

Gene Symbol

IL Receptor

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