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SB 242235

SKU: orb1303186

Description

SB 242235 is a potent and selective inhibitor of p38 MAP kinase, making it a candidate therapeutic for diseases driven by inflammatory cytokines. It has been utilized in research to investigate cytokine signaling pathways in both cellular (in vitro) and animal (in vivo) models of inflammation and autoimmune disorders.

Research Area

Cell Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number193746-75-7
MW353.39
Purity99.13%
FormulaC19H20FN5O
SMILESCOc1nccc(n1)-c1c(ncn1C1CCNCC1)-c1ccc(F)cc1
Targetp38 MAPK,Autophagy
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.66 mM);DMSO:60 mg/mL (169.78 mM)

Bioactivity

Target IC50
p38 MAPk:1.0 μM

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Autophagy, inhibit, Inhibitor, SB242235, SB-242235, SB 242235, p38MAPK, p38 MAPK

Similar Products

  • SB-242235 [orb1225798]

    >98% (HPLC)

    193746-75-7

    353.3934

    C19H20FN5O

    50 mg, 100 mg, 2 mg, 5 mg, 25 mg, 10 mg, 1 g, 500 mg, 200 mg
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Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

No computed properties available.

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Protocol Information

SB 242235 (orb1303186)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

2 mg
$ 80.00
5 mg
$ 110.00
1 ml x 10 mM (in DMSO)
$ 120.00
10 mg
$ 160.00
25 mg
$ 290.00
50 mg
$ 420.00
100 mg
$ 610.00
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