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SC239

SKU: orb2279072

Description

SC239 is a drug-linker conjugate for ADC development, combining the tubulin inhibitor SC209 with a cleavable Val-Cit-PABC linker and a DBCO group for site-specific conjugation. It demonstrates potent cytotoxicity in vitro, particularly in Igrov1 cells with low FolRα expression, supporting research into targeted cancer therapies.

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Key Properties

CAS Number1977557-97-3
MW1181.42
FormulaC65H84N10O11
SMILESC(CCC(N[C@H](C(N[C@H](C(NC1=CC=C(COC(NC2=CC(C([C@@H](C(N[C@H](C(N([C@H](/C=C(/C(O)=O)\C)C(C)C)C)=O)[C@](C)(C)C)=O)NC)(C)C)=CC=C2)=O)C=C1)=O)CCCNC(N)=O)=O)C(C)C)=O)(=O)N3C=4C(C#CC=5C(C3)=CC=CC5)=CC=CC4
TargetDrug-Linker Conjugates for ADC

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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SC239 (orb2279072)

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