SFNGGP-NH2 PAR3 Tethered Ligand (Murine)/Activates PAR1 and PAR2

SKU: orb2692791

Description

SFNGGP-NH2 is a biological active peptide. (PAR-3 is a high-affinity thrombin receptor. PAR-3 mRNA is expressed in the cutaneous mast cells of humans. Protease-Activated Receptors (PARs) have been studied for their roles in itch and their itch-associated response through histamine-dependent/independent pathways have been reported. PAR-3 has been shown not to induce itching alone but possibly in conjunction with PAR-4. Co-expression of PAR-3 and PAR-4 enhances thrombin action suggesting that PAR-3 alone does not mediate transmembrane signaling but instead functions as a cofactor to activate PAR-4.)

Images & Validation

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Key Properties

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Target	Protease Activated Receptor (PAR)
Molecular Weight	576.6
Protein Sequence	SFNGGP-NH2
Purity	≥95%

Storage & Handling

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Expiration Date	6 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

Protease Activated Receptor (PAR)

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