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SGD-1910

SKU: orb1989100

Description

MC-Val-Ala-PBD is a cleavable drug-linker conjugate designed for antibody-drug conjugates (ADCs), incorporating the DNA-crosslinking cytotoxic agent pyrrolobenzodiazepine (PBD). This construct is utilized in research for developing targeted cancer therapies and has been investigated in both in vitro and in vivo experimental models for its antitumor efficacy.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1342820-51-2
MW1089.2
FormulaC60H64N8O12
SMILES[H][C@@]12CC(=CN1C(=O)c1cc(OC)c(OCCCOc3cc4N=C[C@]5([H])CC(=CN5C(=O)c4cc3OC)c3ccc(OC)cc3)cc1N=C2)c1ccc(NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)CCCCCN2C(=O)C=CC2=O)C(C)C)cc1
TargetDrug-Linker Conjugates for ADC,PROTAC Linker

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

SGD-1910 (orb1989100)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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