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Sibiromycin

SKU: orb1691851

Description

Sibiromycin is a natural glycosylated pyrrolobenzodiazepine (PBD) antitumor antibiotic. It functions by forming covalent adducts with guanine residues in the DNA minor groove. This mechanism supports its investigation in biochemical assays and as a lead compound for anticancer drug development in preclinical research.

Research Area

Infectious Disease & Virology, Molecular Biology

Images & Validation

Key Properties

CAS Number12684-33-2
MW475.542
FormulaC24H33N3O7
SMILES[H][C@@]12CC(\C=C\C)=CN1C(=O)c1cc(O[C@@H]3O[C@@H](C)[C@H](NC)[C@@](C)(O)[C@H]3O)c(C)c(O)c1N[C@@H]2O |c:6|
TargetOthers,DNA Alkylator/Crosslinker,Antibiotic

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Sibiromycin (orb1691851)

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