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SP-A (196-215) (human) TFA

SKU: orb1980018

Description

This synthetic peptide, corresponding to residues 196-215 of human Surfactant Protein A, modulates immune responses by suppressing LPS-induced TNF-α release in dendritic cells and enhancing bacterial phagocytosis. In vivo studies demonstrate its therapeutic potential, reducing infection severity and bacterial load in murine models of Pseudomonas aeruginosa pneumonia.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

MW2397.47
FormulaC107H145N29O35.XCF3COOH
SMILES[H]NCC(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@@H](CO)C(N[C@H](C(NCC(N[C@]([C@@H](C)O)([H])C(N1CCC[C@H]1C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@]([C@@H](C)O)([H])C(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CCC(O)=O)C(O)=O)=O)=O)=O)CC2=CC=C(O)C=C2)=O)CC3=CNC4=C3C=CC=C4)=O)=O)=O)CC5=CC=C(O)C=C5)=O)=O)=O)=O)=O)=O)CC(O)=O)=O)=O)CC6=CC=C(O)C=C6)=O)=O)CC7=CC=CC=C7)=O)CC(O)=O)=O.OC(C(F)(F)F)=O

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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SP-A (196-215) (human) TFA (orb1980018)

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