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SPDB-DM4

SKU: orb1987730

Description

SPDB-DM4 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications, employing the maytansine-based payload DM4 (a tubulin inhibitor) connected through a SPDB linker. This compound demonstrates significant anti-tumor efficacy.

Images & Validation

Key Properties

CAS Number1626359-62-3
MW995.59
FormulaC46H63ClN4O14S2
SMILES[H][C@@]12C[C@@](O)(NC(=O)O1)[C@]([H])(OC)\C=C/C=C(C)\Cc1cc(OC)c(Cl)c(c1)N(C)C(=O)C[C@H](OC(=O)[C@H](C)N(C)C(=O)CCC(C)(C)SSCCCC(=O)ON1C(=O)CCC1=O)[C@]1(C)O[C@H]1[C@@H]2C
TargetDrug-Linker Conjugates for ADC

Storage & Handling

Storage-20°C
DisclaimerFor research use only

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Protocol Information

SPDB-DM4 (orb1987730)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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