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SPDB-DM4

SKU: orb1987730

Description

SPDB-DM4 is a maytansinoid-based drug-linker conjugate for constructing antibody-drug conjugates (ADCs). It is widely used in oncology research, where studies demonstrate its potent antitumor activity in both in vitro cytotoxicity assays and in vivo xenograft models.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1626359-62-3
MW995.59
FormulaC46H63ClN4O14S2
SMILES[H][C@@]12C[C@@](O)(NC(=O)O1)[C@]([H])(OC)\C=C/C=C(C)\Cc1cc(OC)c(Cl)c(c1)N(C)C(=O)C[C@H](OC(=O)[C@H](C)N(C)C(=O)CCC(C)(C)SSCCCC(=O)ON1C(=O)CCC1=O)[C@]1(C)O[C@H]1[C@@H]2C
TargetDrug-Linker Conjugates for ADC,PROTAC Linker

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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SPDB-DM4 (orb1987730)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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