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STING modulator-3

SKU: orb1744789

Description

STING modulator-3 is a potent small molecule inhibitor of the R232 STING variant with a Ki of 43.1 nM. It selectively blocks this STING isoform without affecting IRF-3 activation or TNF-β production in THP-1 cells. This compound is a valuable tool for dissecting STING-dependent signaling in immunological and inflammatory research, both in vitro and in vivo.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number2839639-94-8
MW375.39
FormulaC18H17N9O
SMILESCN1C(C2=C3C(=CC(C(N)=O)=N2)N(C)N=C3)=NC(=C1)C=4N(CC#N)N=C(C)C4
TargetOthers,STING

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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STING modulator-3 (orb1744789)

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