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Suprafenacine

SKU: orb1304885

Description

Suprafenacine is a cell-permeable small molecule that destabilizes microtubules by binding at the colchicine site, leading to G2/M phase arrest and apoptosis. It demonstrates selective activity against various cancer cell lines, including those with drug-resistant phenotypes, making it a useful research tool for studying mitotic disruption and anticancer mechanisms in vitro.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number1477482-50-0
MW282.34
Purity99.91% (May vary between batches)
FormulaC16H18N4O
SMILESCC1=CC=C(\C=N\NC(=O)C2=NNC3=C2CCCC3)C=C1
TargetMicrotubule Associated
SolubilityDMSO:2.83 mg/mL (10.02 mM)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Suprafenacine, N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide, microtubule, MicrotubuleAssociated, Microtubule Associated
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Key Properties

No computed properties available.

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Suprafenacine (orb1304885)

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Available Sizes

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1 mg
$ 100.00
2 mg
$ 130.00
1 ml x 10 mM (in DMSO)
$ 180.00
5 mg
$ 180.00
10 mg
$ 230.00
25 mg
$ 380.00
50 mg
$ 520.00
100 mg
$ 720.00
200 mg
$ 930.00
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