Tamoxifen-d3 hydrochloride

SKU: orb3138383

Description

Tamoxifen-d3 hydrochloride is a deuterium-labeled derivative of Tamoxifen (Citrate), which is an orally active selective estrogen receptor modulator (SERM). It inhibits estrogen activity in breast cells while activating estrogen receptors in other cells such as those in bone, liver, and uterus. Tamoxifen Citrate acts as a potent Hsp90 activator, enhancing the ATPase activity of the Hsp90 molecular chaperone. Furthermore, it effectively suppresses infectious EBOV Zaire and Marburg (MARV) viruses with IC50 values of 0.1 μM and 1.8 μM, respectively. Tamoxifen Citrate also stimulates autophagy and induces apoptosis, and is capable of triggering gene knockout in CreER(T2) transgenic mice.

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Key Properties

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Target	Estrogen Receptor/ERR,Autophagy,HSP,Apoptosis

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

Estrogen Receptor/ERR,Autophagy,HSP,Apoptosis

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