TAPI-1 trifluoroacetate (163847-77-6(free base))

SKU: orb1690056

Description

TAPI-1 is a cell-permeable inhibitor of ADAM17/TACE, effectively preventing the ectodomain shedding of cytokine receptors and TNF-α. This compound is widely used in vitro to study inflammatory signaling and has been applied in vivo to investigate models of sepsis and rheumatoid arthritis.

Research Area

Protein Biochemistry

Images & Validation

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Key Properties

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MW	613.62
Purity	98.06%
Formula	C₂₈H₃₈F₃N₅O₇
SMILES	OC(=O)C(F)(F)F.CC(C)CC(CC(=O)NO)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](C)C(=O)NCCN
Target	MMP

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

137963718 ↗

Key Properties

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No computed properties available.

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