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TAPI 2

SKU: orb1679245

Description

This small molecule is a potent ADAM-17/TACE and MMP inhibitor (Ki = 120 nM at ADAM-17). It blocks TNF-α shedding and sensitizes cancer stem cells to 5-FU in vitro, making it a valuable tool for oncology research focused on chemotherapy resistance and inflammatory signaling pathways.

Research Area

Infectious Disease & Virology, Protein Biochemistry

Images & Validation

Key Properties

TargetMMP,SARS-CoV,Others
CAS Number689284-12-6
MW415.54
FormulaC19H37N5O5
SMILES[C@@H](NC([C@@H](CC(NO)=O)CC(C)C)=O)(C(N[C@H](C(NCCN)=O)C)=O)C(C)(C)C

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Documents Download

Datasheet
Product Information
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Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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TAPI 2 (orb1679245)

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